Authors: Siddhartha Roy, Tapas K. Kundu
Categories: Science
Publisher: Elsevier
Published Date: 2021-05-19
Language: en
Description: I. An integrative approach to chemical biology a) Philosophy behind the integrative approach b) Ensembles of molecules possess fundamentally different properties than individual molecules c) Physical tools for studying ensembles and their properties d) Chemical Genetics: A powerful approach to study cellular functions e) Genes and Genomes: An integral entity II. Genes, Genomes and Genome Dynamics a) Genes: The building block Definition, identification, functional genes: an evolution in thoughts and ideas b) Genome: Complexity and Diversity. The organization of genes, the organization of genomes, the structure of chromatin c) Unstable genes: Biology and Chemistry. Unstable loci, why some genes are unstable (chemical and physical perspectives). Biological trigger for jumping genes d) The Dynamic Epigenome: Epigenetic Modifica.
